Model-based quantitative laser Doppler flowmetry in skin

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Model-based quantitative laser Doppler flowmetry in skin.

Laser Doppler flowmetry (LDF) can be used for assessing the microcirculatory perfusion. However, conventional LDF (cLDF) gives only a relative perfusion estimate for an unknown measurement volume, with no information about the blood flow speed distribution. To overcome these limitations, a model-based analysis method for quantitative LDF (qLDF) is proposed. The method uses inverse Monte Carlo t...

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Quantitative Laser Doppler Flowmetry

vii-Abstract Laser Doppler flowmetry (LDF) is virtually the only non-invasive technique, except for other laser speckle based techniques, that enables estimation of the microcirculatory blood flow. The technique was introduced into the field of biomedical engineering in the 1970s, and a rapid evolvement followed during the 1980s with fiber based systems and improved signal analysis. The first i...

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Laser Doppler flowmetry in manual medicine research.

Laser Doppler flowmetry (LDF) is commonly used in combination with reactivity tests to noninvasively evaluate skin sympathetic nerve activity and skin microvascular function. In manual medicine research, LDF has been used as a marker for global peripheral sympathetic nervous system function, but these results should be considered with caution because skin sympathetic nerve activity physiology i...

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Laser Doppler Flowmetry - a Theoretical Framework

Laser Doppler Flowmetry (LDF) is a non-invasive method to estimate the blood perfusion in the microcirculation. The method was first introduced over 30 years ago and has undergone a continuous development since. This work presents a thorough theoretical framework of the technique. It is described in detail how the laser light interacts with the tissue and moving red blood cells, how the light f...

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ژورنال

عنوان ژورنال: Journal of Biomedical Optics

سال: 2010

ISSN: 1083-3668

DOI: 10.1117/1.3484746